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Journal of Experimental Orthopaedics
Fig. 1 | Journal of Experimental Orthopaedics

Fig. 1

From: Diminazene aceturate or losartan ameliorates the functional, radiological and histopathological alterations in knee osteoarthritis rodent model: repurposing of the ACE2/Ang1-7/MasR cascade

Fig. 1

Evaluation of nociception using rotarod (a), knee bend (b) and knee swelling (c) tests. Drugs were administered daily for 21 days. Data are presented as means ± SEM (n = 10). Comparisons among groups were analyzed using one-way ANOVA followed by Tukey post-hoc test and comparisons between groups in knee bend test were analyzed using Kruskal–Wallis test, followed by Dunn's post hoc-test. Data are compared at p < 0.05 with CN (*), OA (#). CN; control, OA; MIA induced osteoarthritis, LOS; losartan treated osteoarthritis and DIZE; diminazene treated osteoarthritis

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